WebInteractions between protomers are illustrated on the basis of oligomeric structures of each AAA+ subgroup. The possible role of conserved motifs in the nucleotide binding pocket … WebAug 22, 2008 · Having chosen biologically relevant motif MHG p-value thresholds, we next compared the KMM motifs found by our motif finder for the TF-condition sets with the motifs published by MacIsaac et al. . For each TF-condition set, we allowed the motif finder to output up to five unique motifs. Only those that passed their sets' bin threshold were ...
An analysis of the positional distribution of DNA motifs in …
WebMar 1, 2024 · Thus, such biologically relevant portions of chemical space may only be accessible by exploiting features encoded and subsequently passed-on through the incorporation of structural motifs generated by secondary metabolite biosynthesising proteins, which themselves share evolutionary conserved structural features. 13 This … WebSep 27, 2024 · Introduction. Biopolymers, such as DNA and protein, perform varying functions based on their primary sequence. Short, repeated sequences, or “motifs” represent functional units within biopolymers that … citizen tour
How biologically relevant are interaction-based modules in …
WebJul 7, 2009 · A unique motif GX{P}[LMQ]X{P}XX{P}X{CIMPVW} was identified as a sufficient condition for peptide binding to Ydj1p. Yeast proteome screen revealed that the … WebSep 9, 2024 · Crosslinking and immunoprecipitation (CLIP) is a method used to identify in vivo RNA–protein binding sites on a transcriptome-wide scale. With the increasing amounts of available data for RNA-binding proteins (RBPs), it is important to understand to what degree the enriched motifs specify the RNA-binding profiles of RBPs in cells. We … MEIRLOP enables enrichment of biologically relevant TF binding motifs where other methods may fixate on nucleotide or dinucleotide sequence bias. On differential H3K27ac data, it achieves superior accuracy over other methods in identifying significant enrichment of motifs known to mediate … See more MEIRLOP is based on a logistic regression model for motif enrichment. At minimum, it accepts a list of scored sequences (in the AME scored FASTA format, with sequence headers consisting of a name and score … See more We started with cell culturing and ChIP-seq for data acquisition. This was followed by differential ChIP-seq bioinformatics analysis comparing stimulated samples vs. unstimulated … See more We started by extracting sequences and scores for differential TSS data previously generated as described in Duttke et al. [38]. We then ran MEIRLOP on the scored TSS sequences. This … See more We started by selecting ENCODE ChIP-seq experiments and extracting scored FASTA files for input into MEIRLOP and AME. Then, we ran … See more dickies shorts flex vs industrial