Cytogenetic effects

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Webcytogenetic subgroups reveals distinct signatures in matched myometrium: transcriptional proﬁling of the t(12;14) and evidence in support ... important to produce an accurate t(12;14) UL-speciﬁc gene list by removing the confounding effects of genotype and environment. Interestingly, myometrium not only clustered away from the tumors, but ...

Cytogenetic effects in lymphocytes from children ... - ScienceDirect

WebAug 5, 2003 · The cytogenetic effects of LCT were investigated in humans and in various animal species using different endpoints such as micronucleus (MN) formation, induction of chromosomal aberrations, and sister chromatid exchange [5], [6], [7]. WebFeb 1, 2024 · Cytogenetic methods of biotesting are used to assess the direct and combined effects of metal ions in water. The mitotic index (MI) and the aberrant cell frequency (ACF) are determined in the... small town in tennessee with low crime

Cytogenetic effects of β-particles in Allium cepa cells used as a ...

Web203 Cytogenetic Effects of the Action of Ionizing Radiations on Human Populations Vladimir A. SHEVCHENKO1, Galina P. SNIGIRYOVA2 1 N. I. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow 2 Moscow Research Institute of Diagnostics and Surgery, Ministry of Health and Medical Industry of the Russian … WebAug 19, 2014 · Our findings clearly demonstrate that α-COP exhibited mild cytotoxic effects on N2a-NB cell line. In conclusion, α-COP may have potential as an anticancer agent, … WebEnter the email address you signed up with and we'll email you a reset link. small town in spanish

Cytogenetic effects of antidiabetic drug metformin

No. 26 - Leukemia & Lymphoma Society

WebApr 1, 2024 · The cytogenetic effects of β -irradiation in onion roots with doses of 0.04–1.44 Gy were studied. • The genotoxic potential of brief external exposures to … WebAug 19, 2014 · Alpha-copaene ( α -COP), a tricyclic sesquiterpene, is present in several essential oils of medicinal and aromatic plants and has antioxidant and antigenotoxic features. Its cytotoxic, cytogenetic and oxidative effects have not been investigated in neuron and N2a neuroblastoma (NB) cell cultures. highways yeovilWebExposed individuals showed a significant increase in the frequency of chromatid and isochromatid deletions in lymphocytes and of MN in oral and urinary epithelial cells. Males were more affected than females, and a higher number of micronucleated oral cells were found among those individuals with skin lesions. small town in ny

"WebNov 23, 2024 · The rates of the most common treatment emergent adverse events (TEAEs) of any grade were similar across risk groups (HR- vs SR-Cyto): thrombocytopenia … " - Cytogenetic effects

Cytogenetic effects

Cytogenetic toxicity of methotrexate in mouse bone marrow

WebDec 12, 1997 · The cytogenetic analysis shows a statistically significant increase of aberrations in children belonging to the first group with respect to the controls. This … WebCytogenetic analysis is the study of the banded pattern of chromosomes during metaphase of the cell cycle. It is carried out on a cell-by-cell basis, and hence mosaicism is easily recognized when only a few cells carry the chromosomal abnormality. This analysis can detect large-scale chromosomal abnormalities, most commonly aneuploidy.

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WebMay 31, 2024 · Ambient air pollution may cause respiratory and cardiovascular diseases and can also result in increased emergency department visits and daily mortality rates … Web[Effect of folinic acid (leucovorin) on cytotoxic and cytogenetic effects of methotrexate] Folia Med Cracov. 1986;27(3-4):239-44. [Article in Polish] Authors K Pieńkowska, J Koziorowska. PMID: 3494651 No abstract available. Publication types Comparative Study ...

WebIts teratogenicity and effects on fetal chromosomes were investigated in mice. Various dose levels of methylmercuric chloride (MMC) were administered via an intragastric tube to pregnant ICR Swiss/Webster mice on day 9 of gestation. ... Cytogenetic studies revealed significant clumping of chromosomes in metaphase at all dose levels and the ... WebJan 16, 2024 · Our research shows the potential of using cytogenetic effects in Allium cepa cells as a biological indicator for a first screening of genotoxic damages induced by brief …

WebAug 8, 2024 · Cytogenetic testing is the examination of chromosomes to determine chromosome abnormalities such as aneuploidy and structural abnormalities. A normal … WebMutagenesis vol.17 no.5 pp.411–417, 2002 Cytogenetic and oxidative damage induced in human lymphocytes by platinum, rhodium and palladium compounds Lucia Migliore3, Giada Frenzilli1, Claudia Nesti, Salvador Fortaner 2and Enrico Sabbioni Dipartimento di Scienze dell’Uomo e dell’Ambiente and 1Dipartimento di Morfologia Umana e Biologia Applicata, …

WebMar 24, 2024 · Comet assay and MN were used to evaluate the cytogenetic effects due to their different way of exploring genotoxic effects. The comet assay can detect DNA damage, i.e., single-strand breakage or other aberrations, such as alkali–labile sites, DNA cross-links [ 27, 28 ], and incomplete excision repair events [ 29 ].

WebAug 5, 2003 · Lambda-cyhalothrin (LCT) is a newer pyrethroid insecticide used all over the world. The cytogenetic effects of LCT were investigated in humans and in various … small town in texas 1976WebJan 25, 2024 · ABO Incompatible LDLT for HCC. HPB. Figure 2 From: Sochorová Z, Döbbeler P, Sochor M, Van Rooy J (2024) Octospora Conidiophora … highways yorktonWebThe present study investigates the cytogenetic effects of the fungicide Royal Flo on mitotic cell division in maize ( Zea mays L.) root cells. The maize grains were treated with various fungicide concentrations (50, 70, and 80%) for 20, 24 and 48 h exposure times. small town in texas to retireWebSep 26, 2024 · The aim of the current study was to obtain estimations of genome damage after CT scans in 42 non-cancer patients and to conduct a comparison of the results with … small town in texas to liveWebStudies showed that the risk of stomach cancer and other gastrointestinal malignancies from radon in drinking water is small. Studies of the genetic and cytogenetic effects of indoor radon yielded equivocal results; while radon exposure in miners induces gene mutations and chromosomal aberrations. small town in texas movieWebMar 31, 2024 · Biomonitoring of genotoxic hazards has been reported in several studies by the use of different genotoxicity endpoints, such as analysis of primary DNA damage (by … highways your way staffordshireWebThe results show that radiation exposure induces a stimulatory response at lower dose and an inhibitory response at higher dose on the mitotic activity of wet seeds and seedlings. … highways yorkshire