WebGranzyme K Expressed by Classically Activated Macrophages Contributes to Inflammation and Impaired Remodeling Christopher T. Turner1,2, Matthew R. Zeglinski1,2, Katlyn C. Richardson1,2, Hongyan Zhao1,2, Yue Shen1,2, Anthony Papp3,5, Phillip I. Bird4 and David J. Granville1,2,5 Granzyme K (GzmK), traditionally described as a pro … Webgranzyme K (GM6C3) is a mouse monoclonal antibody raised against granzyme K of human origin. PRODUCT Each vial contains 200 µg IgG 2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin. granzyme K (GM6C3) is available conjugated to agarose (sc-56125 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; to HRP (sc …
Granzyme K Expressed by Classically Activated Macrophages ... - …
WebApr 1, 2024 · Granzyme K (GzmK), traditionally described as a pro-apoptotic, granule-secreted serine protease, has been proposed to promote inflammation. ... M1 … WebOct 1, 2005 · It is concluded that GzmK protein is produced by cytotoxic cells, and just as GzmA and B it can be released in a soluble form into the extracellular space. Granzymes are serine proteases released from the granules of cytotoxic lymphocytes during the induction of apoptosis. To evaluate the physiologic role of human granzyme K (GzmK), … brake service fairfax va
Frontiers Granzyme B Expression in Visceral Adipose Tissue …
WebMay 1, 2024 · GrK, granzyme K; CCL3 or MIP-1-alpha, Macrophage in fl ammatory protein-1 a. Bouwman et al. Granzyme K Frontiers in Immunology www.frontiersin.org May 2024 Volume 12 Article 677707 5 WebNov 18, 2024 · Granzyme B (GrB) is a serine protease produced by immune and non-immune cells, able to promote multiple processes, like apoptosis, inflammation, extracellular matrix remodeling and fibrosis. GrB expression in visceral adipose tissue (VAT) was associated with tissue damage, local inflammation and insulin resistance in obesity … WebApr 13, 2024 · Androgen deprivation therapy (ADT) is a standard therapy for prostate cancer (PCa). Though disseminated disease is initially sensitive to ADT, an important fraction of the patients progresses to castration-resistant prostate cancer (CRPC). For this reason, the identification of novel effective therapies for treating CRPC is needed. … brake service inc garden city