Small ubiquitin-related modifier 2

Author: fmet

August undefined, 2024

WebSep 29, 2024 · Small ubiquitin-related modifier (SUMO) is one such modifier. Therefore, ubiquitination and sumoylation are two post-translational modifications. Ubiquitination marks proteins for degradation. In contrast, sumoylation is not used to mark proteins for degradation. Both modifications regulate protein localization and activity. WebNov 26, 2024 · Small ubiquitin-related modifiers (SUMOs) are a group of proteins known to greatly influence various cellular biological processes, 4 such as the cell cycle, signal …

Hepatic Small Ubiquitin-Related Modifier (SUMO)-Specific …

WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in … WebMar 21, 2024 · SUMO2 (Small Ubiquitin Like Modifier 2) is a Protein Coding gene. Diseases associated with SUMO2 include Phlyctenulosis . Among its related pathways are Transport of the SLBP independent Mature mRNA and Homology Directed Repair . Gene Ontology (GO) annotations related to this gene include RNA binding and SUMO transferase activity . ons birth rates 2021

6613 - Gene ResultSUMO2 small ubiquitin like modifier 2 [ (human)]

WebSmall ubiquitin-related modifier (SUMO)-specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, signal transduction, … WebSUMOylation by generating mature small ubiquitin-related modifiers (SUMO) for protein conjugation (endopeptidase ... SUMO protease but functions on another small ubiquitin-re-latedproteinknownasNedd8(6,7).Thedefiningcharacteristic ... SUMO, small ubiquitin-like modifier; AFC, 7-amino-4-trifluoromethyl coumarin; DUB, de-ubiquitinating enzyme; WebSUMO (small ubiquitin-related modifier) proteins are ∼ 10-kD polypeptides that function as reversible post-translational protein modifiers. They form isopeptide bonds with ɛ-amino … ons birth characteristics 2021

Small ubiquitin-related modifier 2 affects the intracellular survival ...

SUMO protein - Wikipedia

WebMar 15, 2012 · SUMO (small ubiquitin-related modifier) conjugation is a reversible three-step process of protein post-translational modifications mediating protein-protein interactions, subcellular compartmentalization and regulation of transcriptional events. Among divergent transcription factors regulated by SUMOylation and deSUMOylation, the … In molecular biology, SUMO (Small Ubiquitin-like Modifier) proteins are a family of small proteins that are covalently attached to and detached from other proteins in cells to modify their function. This process is called SUMOylation (sometimes written sumoylation). SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional re… in your grave band lyricsWebSmall ubiquitin-like modifier 3 (SUMO3) is encoded by the gene mapped to human chromosome 21q22.3. The protein belongs to the ubiquitin-like protein family and is expressed mainly in cytoplasm. [ 1] [ 2] Immunogen human SUMO3 fusion protein Application Monoclonal Anti-Sumo-2/3 has been used in immunoblotting and … ons birmingham

"WebFeb 22, 2005 · Importantly, Sp100 and PML are both covalently linked to small ubiquitin-related modifiers (SUMOs). Therefore, we investigated whether SUMO proteins are independent autoantigens in PBC and studied 99 PBC sera samples for reactivity against NDs, PML, and Sp100, as well as against SUMO-2 and SUMO-1 recombinant proteins. " - Small ubiquitin-related modifier 2

Small ubiquitin-related modifier 2

WebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, … WebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the …

Did you know?

UniProt P61956 · SUMO2_HUMAN Protein Small ubiquitin-related modifier 2 Gene SUMO2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 95 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST … See more This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. 1. Name1 2. See … See more WebFeb 11, 2011 · Small ubiquitin-related modifier (SUMO)-1 promotes glycolysis in hypoxia Under conditions of hypoxia, most eukaryotic cells undergo a shift in metabolic strategy, which involves increased flux through the glycolytic pathway. Although this is critical for bioenergetic homeostasis, the underlying mechanisms have remained incompletely …

WebSmall ubiquitin-related modifier 2/3 interacts with p65 and stabilizes it in the cytoplasm in HBV-associated hepatocellular carcinoma. Data show that substantial increases in the binding of small ubiquitin-like modifier 2 (SUMO-2) to active DNA regulatory elements in response to heat stress. WebAbstract. Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds of proteins involved in processes such as chromatin organization, transcription, DNA repair, macromolecular assembly, protein homeostasis, trafficking ...

WebJul 26, 2024 · together, this work shows that small ubiquitin-related modifier-2 modification of NF-jB2/p65 is essential for the survival of Brucella abortus 2308 inside macrophages. … WebApr 13, 2024 · Tumor cells are known to produce high amounts of intracellular lipids, leading to increased levels of fatty acids, cholesterol and membrane phospholipids. Death domain-associated protein (DAXX) is a small ubiquitin-related modifier (SUMO)-binding protein that plays a role in transcription regulation by interacting with transcription factors such as …

WebMay 2, 2024 · Small ubiquitin-related modifier (SUMO)–specific protease 2 (SENP2) is responsible for de-SUMOylation of target protein, with broad effects on cell growth, …

WebMay 1, 2009 · The present study aimed to produce and pathophysiologically evaluate the metallothionein (MT) fusion protein. A recombinant plasmid containing DNA segment coding the pET-glutathione transferase (GST)-small ubiquitin-related modifier (SUMO)-MT fusion protein was inserted into Escherichia coli for expression. The expression level of … in your hairWebSUMOylation is a reversible PTM that entails covalent ligation of small ubiquitin-related modifier (SUMO) groups at specific lysine residues. The SUMO family members (SUMO-1, -2, -3, and -4) belong to the group of ubiquitin-like protein-modifying enzymes. Similarly to ubiquitination, SUMOylation is a multistep process that involves an ... ons birmingham populationWebSmall ubiquitin-related modifier 2 is a protein that in humans is encoded by the SUMO2 gene. [5] Function [ edit] This gene encodes a protein that is a member of the SUMO … ons birth rates 2022WebProtein target information for Small ubiquitin-related modifier 2 (tropical clawed frog). Find diseases associated with this biological target and compounds tested against it in bioassay experiments. in your hands 2010 filmWebOct 1, 2024 · Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates multiple biological processes, including cell division, DNA … in your hand mediaWebSep 23, 2004 · Covalent attachment of small proteins to substrates can regulate protein activity in eukaryotes. SUMO, the s mall u biquitin-related mo difier, can be covalently linked to a broad spectrum of substrates. An understanding of … in your hand on your hand ons births 2020