WebAug 20, 2014 · The term “tachyphylaxis” is not appropriate to represent TSA or RBSS because tachyphylaxis is usually used to faster-onset responses than TSA or RBSS. If the term tachyphylaxis in the guidelines is used only in the original meaning – as in, the effect of epinephrine becomes weakened in the blood vessels because of frequent administration ... WebWhat are mechanisms of drug tolerance? Dispositional (metabolic) tolerance Reduced responsiveness (pharmacodynamic) tolerance Behavioral (context-specific) tolerance What causes dispositional (metabolic) tolerance? Increased target tissue clearance by induction of metabolic enzymes. What is the time frame for dispositional (metabolic) tolerance?
Use of vasopressors and inotropes - UpToDate
WebTachyphylaxis to the neuromuscular blocking effects of suxamethonium is associated with repeated doses. Prolonged exposure of the neuromuscular junction to suxamethonium (resulting from repeated bolus injections or during an infusion of the drug, or as a consequence of delayed hydrolysis subsequent to genetic or acquired … WebJun 1, 2001 · It manifests as a loss of acid inhibitory efficacy and is also a class effect. It is present within a few doses but is not progressive after 29 days. Rebound acid hypersecretion after proton pump inhibitors has been shown for both basal and maximal acid output by 14 days after treatment. clash thomas peters
Differential Opioid Tolerance and Opioid-induced …
WebIt may be possible to restore the response by increasing the dose (or concentration) of the drug but, in some cases, the tissues may become completely refractory to its effect. The term tachyphylaxis is used to describe desensitization that occurs very rapidly, sometimes with the initial dose. WebMay 26, 2024 · Still, there are enigmatic aspects about SSRIs, such as the difficulty to predict effect in individual patients, inter-individual differences in side effect, tachyphylaxis (a … WebJun 18, 2024 · Tachyphylaxis is a decrease in the therapeutic effect of medications when they are re—administered. The condition is most often found with the use of … download free nfs mw 2005 trainer/teleporter